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The U.S. chemicals industry entered Q1 2025 on uncertain footing, navigating a complex landscape shaped by economic volatility, regulatory transitions, and global trade frictions. Rising input costs, tightening financial conditions, and shifting valuation norms marked the quarter. Private equity and corporate buyers remained active, selectively deploying capital in undervalued segments. Meanwhile, middle-market M&A stayed resilient, buoyed by significant liquidity reserves, strategic reshoring momentum, and an improving regulatory environment. Despite near-term uncertainties, the long-term fundamentals for chemicals M&A remain strong, particularly in specialty and resilient subsectors where strategic acquirers seek growth via consolidation.